Researchers back cancer-fighting properties of papaya

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Researchers back cancer-fighting properties of papaya

AFP/File ¡V A street vendor prepares papaya for her daily customers in Yangon. Researchers said Tuesday that papaya ¡K

MIAMI (AFP) ¡V Researchers said Tuesday that papaya leaf extract and its tea have dramatic cancer-fighting properties against a broad range of tumors, backing a belief held in a number of folk traditions.

University of Florida researcher Nam Dang and colleagues in Japan, in a report published in the Journal of Ethnopharmacology, documented papaya's anticancer effect against tumors of the cervix, breast, liver, lung and pancreas.

The researchers used an extract made from dried papaya leaves, and the effects were stronger when cells received larger doses of papaya leaf tea.

Dang and the other scientists showed that papaya leaf extract boosts the production of key signaling molecules called Th1-type cytokines, which help regulate the immune system.

This could lead to therapeutic treatments that use the immune system to fight cancers, they said in the February issue of the journal and released Tuesday by the university.

Papaya has been used as a folk remedy for a variety of ailments in many parts of the world, especially Asia.

Deng said the results are consistent with reports from indigenous populations in Australia and his native Vietnam.

The researchers said papaya extract did not have any toxic effects on normal cells, avoiding a common side effect of many cancer treatments.

Researchers exposed 10 different types of cancer cell cultures to four strengths of papaya leaf extract and measured the effect after 24 hours. Papaya slowed the growth of tumors in all the cultures.

Dang and a colleague have applied to patent the process to distill the papaya extract through the University of Tokyo.

Division of Hematology and Oncology

Nam H. Dang, MD, PhD

Nam H. Dang, MD, PhD
Division of Hematology/Oncology
Professor and Deputy Division Chief
University of Florida Shands Cancer Center
Director, UFSCC Clinical Trials Office

1600 SW Archer Road- Box 100278
Gainesville, FL 32610

Nam H. Dang, MD, PhD is a board certified medical oncologist with expertise in the study and treatment of lymphoma and chronic lymphocytic leukemia (CLL).  He is Professor and Deputy Chief of the Division of Hematology & Oncology as well as Director of the University of Florida Shands Cancer Center Clinical Trials Office. 

Training:

Degree
Program

Institution

Field/Specialty

A.B. (Magna Cum Laude)

Harvard University

Biochemical Sciences

PhD

Harvard University

Immunology

MD (Magna Cum Laude)  

Harvard Medical School

Medicine

Residency

Massachusetts General Hospital

Internal Medicine

Fellowship

Dana-Farber Cancer Institute

Medical Oncology

Clinical Interests:

Diagnosis and Treatment of Lymphoma and Chronic Lymphocytic Leukemia (CLL)

Research Interests:

Dr Dang¡¦s primary research effort emphasizes the development of novel treatment strategies for patients with lymphoma/CLL through the identification of new targets and the utilization of novel targeted therapies.  To achieve this aim, he has conducted multiple clinical trials and is active in laboratory research with the goal of translating laboratory findings to the clinical setting for the ultimate benefit of the patient.